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Patricia K Donahoe Selected Research

COVID-19 related adult multisystem inflammatory disease

3/2010Development of an efficiently cleaved, bioactive, highly pure FLAG-tagged recombinant human Mullerian Inhibiting Substance.
3/2007Mullerian-inhibiting substance induces Gro-beta expression in breast cancer cells through a nuclear factor-kappaB-dependent and Smad1-dependent mechanism.
11/2006Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.
10/2006Mullerian inhibiting substance regulates androgen-induced gene expression and growth in prostate cancer cells through a nuclear factor-kappaB-dependent Smad-independent mechanism.
1/2005Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting Substance.

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Patricia K Donahoe Research Topics

Disease

16Neoplasms (Cancer)
03/2017 - 01/2002
10Ovarian Neoplasms (Ovarian Cancer)
03/2017 - 12/2003
5COVID-19 related adult multisystem inflammatory disease
03/2010 - 01/2005
4Breast Neoplasms (Breast Cancer)
01/2010 - 12/2003
3Carcinoma (Carcinomatosis)
06/2012 - 03/2006
3Uterine Cervical Neoplasms (Cancer of the Cervix)
06/2012 - 12/2003
3Persistent Mullerian duct syndrome
09/2010 - 01/2002
3Prostatic Neoplasms (Prostate Cancer)
10/2006 - 01/2002
2Primary Ovarian Insufficiency
12/2021 - 01/2017
2Ascites
08/2015 - 07/2006
2Endometrial Neoplasms (Endometrial Cancer)
05/2015 - 01/2005
2Ovarian Epithelial Carcinoma
09/2014 - 12/2003
2Endometriosis
09/2014 - 09/2012
2Neoplasm Metastasis (Metastasis)
01/2011 - 01/2010
2Disorders of Sex Development (Intersexuality)
08/2003 - 02/2003
2Cryptorchidism (Undescended Testes)
02/2003 - 08/2002
1Infertility (Sterility)
12/2021
1Premature Birth (Birth, Premature)
11/2018
1Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
11/2018
1Wounds and Injuries (Trauma)
03/2017
1Hypogonadism (Hypergonadotropic Hypogonadism)
01/2017
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2016
1Lung Neoplasms (Lung Cancer)
01/2016
1Oligospermia (Oligozoospermia)
03/2013
1Congenital Heart Defects (Congenital Heart Defect)
08/2012
1Congenital Diaphragmatic Hernias
10/2010
1Spermatocele
09/2010
146,XY Disorder of Sex Development (Male Pseudohermaphroditism)
09/2010
1Leiomyoma (Uterine Fibroids)
02/2010
1Carcinogenesis
01/2010
1Teratocarcinoma
10/2007
1Congenital Abnormalities (Deformity)
10/2007
1Chromosome Aberrations (Chromosome Abnormalities)
05/2007
1Tracheomalacia
01/2005
1Leydig Cell Tumor
03/2004
1Hypospadias
08/2003
1Congenital adrenal hyperplasia due to 21 hydroxylase deficiency
08/2003
1Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
08/2003
1Virilism (Virilization)
08/2003

Drug/Important Bio-Agent (IBA)

17anti-Mullerian hormone receptorIBA
08/2015 - 01/2002
16Anti-Mullerian HormoneIBA
08/2015 - 08/2002
7Proteins (Proteins, Gene)FDA Link
03/2017 - 07/2006
6Hormones (Hormone)IBA
11/2018 - 03/2004
4Transforming Growth Factor beta (TGF-beta)IBA
03/2010 - 01/2005
4NF-kappa B (NF-kB)IBA
03/2007 - 01/2002
4AndrogensIBA
10/2006 - 01/2002
3Biological ProductsIBA
06/2012 - 11/2006
3Messenger RNA (mRNA)IBA
06/2012 - 01/2002
3DNA (Deoxyribonucleic Acid)IBA
07/2006 - 01/2002
2CateninsIBA
03/2017 - 09/2010
2Epithelial Cell Adhesion MoleculeIBA
02/2012 - 11/2010
2Doxorubicin (Adriamycin)FDA LinkGeneric
02/2012 - 11/2006
2Pharmaceutical PreparationsIBA
03/2010 - 03/2006
2Coloring Agents (Dyes)IBA
02/2010 - 07/2006
2Paclitaxel (Taxol)FDA LinkGeneric
01/2008 - 11/2006
2Testosterone (Sustanon)FDA Link
08/2003 - 08/2002
1Endocrine DisruptorsIBA
12/2021
1PlasticizersIBA
12/2021
1Small Interfering RNA (siRNA)IBA
03/2017
1Protein Isoforms (Isoforms)IBA
01/2016
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2016
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2016
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2016
1Peptides (Polypeptides)IBA
08/2015
1Recombinant ProteinsIBA
09/2014
1FITC-annexin A5IBA
06/2012
1ThiazolesIBA
06/2012
1Cyclin-Dependent Kinases (cdk Proteins)IBA
02/2012
1Surface Antigens (Surface Antigen)IBA
11/2010
1NucleotidesIBA
10/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2010
1Transcription Factors (Transcription Factor)IBA
01/2010
1pyrazolanthroneIBA
01/2008
1phenyl etherIBA
10/2007
1nitrofenIBA
10/2007
1Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2007
1ChemokinesIBA
03/2007
1Sirolimus (Rapamycin)FDA Link
11/2006
1Cisplatin (Platino)FDA LinkGeneric
11/2006
1bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA
07/2006
1Verapamil (Calan)FDA LinkGeneric
07/2006
1Growth InhibitorsIBA
03/2006
1Antineoplastic Agents (Antineoplastics)IBA
03/2006
1Tumor Viral Antigens (Large T Antigen)IBA
03/2006
1Cell Cycle ProteinsIBA
01/2005
1Immunologic Factors (Immunomodulators)IBA
01/2005
1Glycoproteins (Glycoprotein)IBA
01/2005
1Androgen Antagonists (Antiandrogens)IBA
03/2004
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
12/2003
1CEACAM1 ProteinIBA
12/2003
1Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA
12/2003
1Interferon-gamma (Interferon, gamma)IBA
12/2003
1Hydrocortisone (Cortisol)FDA LinkGeneric
08/2003

Therapy/Procedure

8Therapeutics
08/2015 - 08/2003
2Drug Therapy (Chemotherapy)
01/2017 - 03/2006
1Contraception (Birth Control)
01/2017
1Hysterectomy
02/2010
1Castration
06/2006
1Continuous Positive Airway Pressure
01/2005
1Prostheses and Implants (Prosthesis)
08/2003